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目的 观察血管紧张素Ⅱ受体阻滞剂 (ARB)与血管紧张素转换酶抑制剂 (ACEI)联合治疗充血性心力衰竭 (CHF)的疗效。方法 10 4例CHF患者在常规治疗的基础上 ,随机分成 2组 ,对照组 (A组 )采用ACEI制剂卡托普利治疗 ,治疗组 (B组 )采用ARB制剂科素亚与卡托普利治疗 ,均治疗 4～ 6周。结果 A组总有效率为 82 .6 9% ,B组为 96 .15 % ,两组比较有统计学意义 (P <0 .0 5 )。结论 ARB与ACEI联合治疗CHF比单独使用ACEI疗效更确切。
Objective To observe the curative effect of angiotensin Ⅱ receptor blocker (ARB) and angiotensin converting enzyme inhibitor (ACEI) in the treatment of congestive heart failure (CHF). Methods 10 4 CHF patients were randomly divided into 2 groups on the basis of conventional treatment. The control group (group A) received captopril ACEI. The treatment group (group B) Treatment, are treated for 4 to 6 weeks. Results The total effective rate in group A was 82.69% and in group B was 96.15%. There was a significant difference between the two groups (P <0.05). Conclusion The combination therapy of ARB and ACEI is more effective than ACEI alone.