目的探讨江苏省苏州市≥30岁人群尿微量白蛋白异常与肥胖的关系,为采取相应的干预措施提供参考依据。方法采取多阶段整群随机抽样方法对在苏州市金阊区8个小区抽取的2 889名≥30岁常住居民进行问卷调查、体格检查和实验室检测,并采用logistic回归模型分析尿微量白蛋白异常与肥胖的关联性。结果苏州市调查的2 889名≥30岁人群中,尿微量白蛋白异常者446例,检出率为15.44%;尿微量白蛋白异常组与正常组人群比较,体质指数(BMI:25.3 vs 24.4)、腰围(WC:84.0 vs 82.0)、腰臀比(WHR:0.88 vs 0.87)的水平均高于正常组(P<0.01),以这3个指标定义的肥胖和中心性肥胖率均高于正常组(P<0.001);在调整性别、年龄、文化程度、婚姻状况、吸烟、饮酒、血糖、收缩压、舒张压、总胆固醇、甘油三酯、血清尿酸等因素后,多因素logistic回归分析结果显示,BMI肥胖者(OR=1.610,95%CI=1.189~2.181)和WHR中心性肥胖者(OR=1.349,95%CI=1.078~1.688)均可增加≥30岁人群尿微量白蛋白异常的危险性;当BMI肥胖和WHR中心性肥胖者同时存在时,≥30岁人群尿微量白蛋白异常的危险性为无BMI肥胖和WHR中心性肥胖者的1.937倍(OR=1.937,95%CI=1.370~2.740)。结论肥胖是尿微量白蛋白异常的危险因素。 Objective To investigate the relationship between urinary albumin abnormalities and obesity in people aged 30 years and older in Suzhou City, Jiangsu Province, and to provide a reference for taking appropriate interventions. Methods A multistage cluster random sampling method was used to survey 2 889 residents aged ≥30 years old in 8 districts of Jinli District, Suzhou. Physical examination and laboratory tests were performed. Logistic regression analysis was used to analyze urine microalbumin Abnormal and obesity association. Results Among 2 889 persons ≥30 years of age surveyed in Suzhou City, 446 cases of abnormal urine microalbuminuria were detected, the detection rate was 15.44%. Compared with the normal group, the body mass index (BMI: 25.3 vs 24.4 ), Waist circumference (WC: 84.0 vs 82.0) and WHR (WHR: 0.88 vs 0.87) were higher than those in the normal group (P <0.01). The obesity and central obesity rates Normal group (P <0.001). After adjusting for gender, age, education, marital status, smoking, alcohol consumption, blood sugar, systolic blood pressure, diastolic blood pressure, total cholesterol, triglyceride, serum uric acid and other factors, multivariate logistic regression analysis The results showed that patients with BMI obesity (OR = 1.610, 95% CI = 1.189-2.18) and WHR central obesity (OR = 1.349, 95% CI = 1.078-1.68) increased urine microalbuminuria Risk of urinary microalbuminuria in people ≥30 years old was 1.937 times more likely to be free from BMI obesity and WHR central obesity (OR = 1.937, 95% CI) when both BMI obesity and WHR central obesity were present = 1.370 ~ 2.740). Conclusion Obesity is a risk factor of urinary microalbumin abnormality.