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目的观察米索前列醇预防剖宫产术后出血的疗效。方法选择200例剖宫产者,随机分为米索前列醇组(简称米索组)和催产素组,每组各100例。米索组术后(即手术结束后)予米索前列醇400 μg纳肛,催产素组于术后立即给予催产素20 U+5%葡萄糖注射液500 ml静脉点滴,分别观察两组产后2 h和 24 h出血量、用药后产妇血压及副反应的差异。结果术后2 h出血量,米索组显著少于催产素组(P<0.05);两组术后血压变化差异无统计学意义(P>0.05);副反应两组比较,差异无统计学意义(P>0.05)。结论米索前列醇预防剖宫产术后出血效果较催产素好。
Objective To observe the effect of misoprostol in preventing bleeding after cesarean section. Methods 200 cases of cesarean section were selected and randomly divided into misoprostol group (misoprostol group) and oxytocin group, 100 cases in each group. Misoprostol group received 400 μg of misoprostol postoperatively (ie, after the operation was finished), oxytocin group was given 500 ml of oxytocin 20 U + 5% dextrose injection immediately after operation. The postpartum 2 h and 24 h bleeding, maternal blood pressure and adverse reactions after treatment. Results The amount of bleeding at 2 h after operation was significantly lower in the misoprostol group than in the oxytocin group (P <0.05). There was no significant difference in postoperative blood pressure between the two groups (P> 0.05). There was no significant difference between the two groups Significance (P> 0.05). Conclusion Misoprostol is better than oxytocin in preventing bleeding after cesarean section.