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目的探讨黛力新联合奥美拉唑对慢性胃炎伴有反流性食管炎的临床治疗效果。方法选取四川省川北医学院附属医院2014年3月至2016年2月收治的320例慢性胃炎伴反流性食管炎患者为研究对象,根据治疗方案的不同将其分为治疗组和对照组,治疗组的治疗方案为黛力新联合奥美拉唑、莫沙必利,对照组为奥美拉唑联合莫沙必利,治疗1个月和2个月后对两组患者的内镜检查、反流性食管炎症状积分、焦虑和抑郁情绪的改善等方面进行对比分析。结果治疗1个月和2个月时,治疗组患者的内镜检查结果、焦虑、抑郁情绪、流性食管炎的症状积分均优于对照组,且组间差异具有统计学意义P<0.05。结论黛力新联合奥美拉唑能够有效促进慢性胃炎伴反流性食管炎患者的临床康复,改善病因性的焦虑和抑郁症状,值得临床推广应用。
Objective To investigate the clinical effect of combination of Deanin and omeprazole on chronic gastritis with reflux esophagitis. Methods A total of 320 patients with chronic gastritis with reflux esophagitis admitted from March 2014 to February 2016 in the Affiliated Hospital of Sichuan North Medical College were selected as the study subjects and divided into treatment group and control group according to different treatment plans. The treatment group for the treatment of Dean-new combination of omeprazole, mosapride, the control group omeprazole combined mosapride, treatment for 1 month and 2 months after the endoscopic examination of two groups of patients , Reflux esophagitis symptom scores, anxiety and depression and other aspects of the improvement of comparative analysis. Results At 1 month and 2 months, the symptom scores of endoscopy, anxiety, depression and esophagitis in the treatment group were better than those in the control group, and the difference between the two groups was statistically significant (P <0.05). Conclusion Deanxit combined with omeprazole can effectively promote the clinical rehabilitation of patients with chronic gastritis and reflux esophagitis and improve anxiety and depressive symptoms of etiology, worthy of clinical application.