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目的:探讨乙二胺四乙酸对血细胞分析仪血小板计数结果的影响。方法:对56例乙二胺四乙酸(EDTA)依赖性血小板减低症患者分别采用枸橼酸钠真空抗凝管采血、许汝和血小板稀释液稀释后测定。结果:乙二胺四乙酸抗凝血与枸橼酸钠抗凝血、许汝和血小板稀释液手工法测定的血小板数有统计学差异。结论:EDTA抗凝剂可导致血小板发生聚集而引起血小板结果的假性减少,临床工作中应引起高度重视,避免误诊。
Objective: To investigate the effect of ethylenediaminetetraacetic acid on platelet count results of hematology analyzer. Methods: Fifty-six patients with EDTA-dependent thrombocytopenia were collected with sodium citrate vacuum anticoagulant tubes and diluted with platelet diluent Xu et al. Results: There was a significant difference in the number of platelets between ethylenediaminetetraacetic acid anticoagulant and sodium citrate anticoagulant, Xu Ru and platelet diluent manual method. Conclusion: EDTA anticoagulant can cause platelet aggregation and cause the false reduction of platelet results, which should be paid more attention to in clinical practice to avoid misdiagnosis.