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由于本病主要为冠状血流的微循环障碍,为改善心肌的微循环,我们采用了低分子右旋糖酐为主治疗慢型克山病。我们收治的20例病人,均按全国制定慢型克山病诊断标准,随机抽样设观察组和对照组,二组均为女性,观察组15—40岁(平均28岁),病程6月—15年(平均3年),心功Ⅳ级2人,Ⅲ级7人,Ⅱ级1人,合并腹水3人,早期肝硬化1人;对照组15—46岁(平均27.5岁),病程1—10年(平均3.1年),心功Ⅳ级3人,Ⅲ级5人,Ⅱ级2人,合并腹水4人。治疗采用减轻心脏负担、强心、利尿,观察组加用低分子右旋糖酐500毫升静注,每日一次六日为一疗程。观察组病例用2—5个疗程,部分观察病例每日加用20—40毫克多巴胺;对照组病例每日加用12.5％丙种维生素20—40毫升静注,均
As the disease is mainly microcirculation of coronary blood flow, in order to improve myocardial microcirculation, we used low molecular weight dextran for the treatment of chronic Keshan disease. We treated 20 patients, according to the national development of chronic Keshan disease diagnostic criteria were randomly divided into observation group and control group, both were female, observation group 15-40 years (mean 28 years), duration of June - 15 years (average 3 years), 2 heart-work grade Ⅳ, 7 grade Ⅲ, 1 grade Ⅱ, 3 ascites and 1 cirrhosis; control group 15-46 years (mean 27.5 years), duration 1 - 10 years (average 3.1 years), heart function Ⅳ grade 3, Ⅲ grade 5, Ⅱ grade 2, combined with 4 ascites. Treatment to reduce the burden on the heart, cardiac, diuretic, observation group plus low molecular weight dextran 500ml intravenous injection, once daily for six days for a course of treatment. Observed group of patients with 2-5 courses of treatment, some observed cases daily plus 20-40 mg of dopamine; control group cases daily plus 12.5% vitamin C 20-40 ml intravenous injection were