姜夏脐疗加口含姜片减轻乳腺癌化疗后副反应的研究

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目的:观察姜夏脐疗加口含姜片减轻乳腺癌化疗后副反应的效果。方法:将乳腺癌术后TAC方案化疗患者80例随机分为治疗组和对照组各40例。治疗组除常规用恩丹西酮静脉注射外,取法半夏粉10 g以生姜汁5 m L拌成泥状,贴敷于患者神阙穴,用输液贴外敷固定贴敷6 h,每日更换1次,至化疗结束;对照组采用恩丹西酮静脉注射,化疗开始前0.5 h静脉推注,1次/d,持续至化疗结束。结果:对照组化疗后恶心0度4例,Ⅳ度8例;治疗组0度14例,Ⅳ度5例。呕吐对照组0度3例,Ⅳ度9例;治疗组0度12例,Ⅳ度5例。两组化疗后恶心、呕吐程度比较,差异均有统计学意义(P<0.05)。治疗组治疗后症状检测量表评分和焦虑评分均优于对照组(P<0.05)。结论:姜夏脐疗加口含姜片两种中医外治法预防或减轻乳腺癌患者化疗后恶心呕吐反应的效果良好,可提高乳腺癌患者化疗期间生活质量。 Objective: To observe the effects of ginger navel therapy plus ginger tablets in reducing side effects after chemotherapy of breast cancer. Methods: Eighty patients with postoperative TAC regimen of breast cancer were randomly divided into treatment group (40 cases) and control group (40 cases). In addition to routine treatment with ondansetron intravenously, taking 10 g of Pinellia powder ginger juice 5 m L mixed mud paste, apply to patients with Shenque acupoints, fixed with transfusion external application sticking 6 h, daily Replaced once, to the end of chemotherapy; control group with ondansetron intravenously, 0.5 h before chemotherapy began intravenous bolus, 1 / d, until the end of chemotherapy. Results: In the control group, there were 4 cases with 0 degree of nausea and 8 cases with grade Ⅳ after chemotherapy. The treatment group had 0 degree 14 cases and Ⅳ degree 5 cases. Vomiting control group 0 degrees in 3 cases, Ⅳ degree in 9 cases; treatment group 0 degrees in 12 cases, Ⅳ degrees in 5 cases. Nausea and vomiting after chemotherapy in both groups, the difference was statistically significant (P <0.05). After treatment, the symptom checklist score and anxiety score of the treatment group were better than those of the control group (P <0.05). Conclusion: Jiangxia navel treatment plus Jiangmizhimen two kinds of traditional Chinese medicine to prevent or reduce breast cancer patients with chemotherapy after nausea and vomiting good response, can improve the quality of life of patients with breast cancer during chemotherapy.
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