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目的研究缺血性脑血管病中血清组织因子(tissuefactor,TF)及组织因子途径抑制物(tissue factor pathway inhibitor,TFPI)抗原含量与有无颈动脉狭窄的关系。方法采用ELISA法检测血清中TF、TFPI抗原含量。结果在缺血性脑血管病患者中,颈内动脉狭窄组TFPI抗原含量比无狭窄组低,有显著性差异(p?0.05)。结论TFPI抗原含量与有无颈动脉狭窄有关,说明TFPI抗原含量与缺血性脑血管病的危险因素有关。
Objective To investigate the relationship between the levels of tissue factor (TF) and tissue factor pathway inhibitor (TFPI) antigen in the presence or absence of carotid artery stenosis in ischemic cerebrovascular disease. Methods The levels of TF and TFPI in serum were detected by ELISA. Results In patients with ischemic cerebrovascular disease, TFPI antigen content in carotid artery stenosis group was lower than that in non-stenosis group (p <0.05). Conclusion TFPI antigen content with or without carotid artery stenosis, indicating TFPI antigen content and ischemic cerebrovascular disease risk factors.