Refsum综合征又称遗传性共济失调性多发性神经炎。我们在临床上遇见1例，报道如．下。患者女，49岁，1992年8月29日入院。自1985年10月无明显诱因下出现右拇指发麻，逐渐向右肘部发展，半年后左手也麻至肘部，再以后右下肢无力，左下肢发麻，均从远端向近端发展，最后四肢均发 Refsum syndrome, also known as hereditary ataxia polyneuritis. We met in the clinical case of 1 reported. under. Female patient, 49 years old, admitted to hospital on August 29, 1992. Since October 1985 there is no obvious incentive to appear under the right thumb numb, and gradually to the right elbow development, six months after the left hemp to the elbow, and then after the right lower limb weakness, left lower limb numb, both from the distal to the proximal development The last four limbs are made