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初发糖尿病患者64例,随机分为2组:对照组32例,采用多次皮下注射胰岛素;治疗组32例,采用持续胰岛素泵强化治疗,观察治疗期间空腹血糖和餐后血糖的达标时间,以及胰岛素用量和低血糖反应发生率。结果治疗后2组患者空腹血糖和餐后2小时血糖均较治疗前明显下降,但血糖控制指标治疗组与对照组比较具有统计学差异(P<0.05,P=0.047、0.021),且治疗组较对照组在达标时间(P<0.05,P=0.025)、胰岛素日用量(P<0.05,P=0.034)以及低血糖反应(P<0.05,P=0.003)多方面具有统计学差异。结论对于初诊糖尿病患者,早期应用胰岛素泵强化治疗可以缩短血糖达标时间、减少胰岛素用量和低血糖反应。
Sixty-four patients with primary diabetes mellitus were randomly divided into two groups: control group (n = 32), multiple subcutaneous injections of insulin; treatment group (n = 32), continuous insulin pump intensive treatment, observation of fasting blood glucose and postprandial blood glucose during treatment, As well as the amount of insulin and the incidence of hypoglycemic reactions. Results After treatment, fasting blood glucose and postprandial 2-hour postprandial blood glucose in both groups were significantly lower than those before treatment, but there was a significant difference between the two groups in the treatment of glycemic control (P <0.05, P = 0.047,0.021) (P <0.05, P = 0.025), insulin daily dosage (P <0.05, P = 0.034) and hypoglycemic response (P <0.05, P = 0.003) compared with the control group. Conclusion For newly diagnosed patients with diabetes, early treatment with insulin pump can shorten the blood glucose compliance time, reduce insulin dosage and hypoglycemia.