本文简要概述了常用致突物检测方法近年来的发展及完善。Ames试验中增加了对某些种类物质更敏感的菌株:对多环芳烃敏感的TA98/l,8DNP6,对硝基芳香胺敏感的YG 1021和YG 1026、YG1024和YG 1029,对烷化剂敏感的YG 7108和YG7113。出现了一些改良的方法:TLC/Ames法、微量悬浮法、微量波动同时检测法等。这些新菌种、新方法的应用,提高了Ames的敏感性,扩大了其应用范围,简化了操作程序,使之更适用于进行大量、快速筛检。SOS法有较大发展,文中详细介绍了原 This article gives a brief overview of the development and improvement of the commonly used methods for detection of bursts in recent years. Ames test adds strains that are more sensitive to certain species: TA98 / 1, 8DNP6 susceptible to PAHs, YG 1021 and YG 1026, YG1024 and YG 1029 sensitive to nitroaromatic amines, are sensitive to alkylating agents YG 7108 and YG7113. There have been some improved methods: TLC / Ames method, micro-suspension method, simultaneous micro-fluctuation detection method. The application of these new strains and new methods has increased the sensitivity of Ames, expanded its range of applications and simplified the procedure, making it more suitable for large-scale, rapid screening. SOS law has greater development, the article details the original