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目的:考察沙美特罗的急性毒性。方法:本试验采用沙美特罗经腹腔注射后,观察10日,记录小白鼠中毒症状和死亡数。结果:用综合法计算出沙美特罗的LD50及其95%的可信限为:LD50=200.68mg/kg±22.8mg/kg。结论:沙美特罗具有较低的毒性。
Objective: To investigate the acute toxicity of salmeterol. Methods: After the experiment with salmeterol injection by intraperitoneal injection, observed on the 10th, record the symptoms and deaths of mice poisoning. Results: The integrated method was used to calculate the LD50 of salmeterol and its 95% confidence limit: LD50 = 200.68 mg / kg ± 22.8 mg / kg. Conclusion: Salmeterol is less toxic.