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地塞米松磷酸钠滴眼剂为中国药典95版收载的眼科常用制剂。该制剂与抗生素合用具有很好的抗炎效果。但地塞米松磷酸钠为光敏感物质,在生产和贮存过程中易发生光化降解反应,严重地影响了该制剂的稳定性。本文从稳定剂和包装容器两方面对该制剂进行了改进,通过抗氧化和避光两种手
Dexamethasone sodium phosphate eye drops for the Chinese Pharmacopoeia 95 version of ophthalmic preparations contained. This preparation has good anti-inflammatory effect in combination with antibiotics. However, dexamethasone sodium phosphate is a light-sensitive substance, which is prone to photodegradation during production and storage, and seriously affects the stability of the formulation. This article from stabilizing agent and packaging container both improved the preparation, through the antioxidant and dark two kinds of hands