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目的：分析增加野宽提高食管癌放疗疗效的可能性。方法在1995年6月～1997年5月我科住院放疗的食管癌患者中，选取病变长度＞3cm、未手术、放疗剂量≥40Gy、资料完整者共51例。其中加宽野照射15例（加宽组），常规野照射36例（对照组）。体外照射总剂量40～75Gy（64.31±6.70Gy）。对加宽组和对照组的疗效进行组间比较并按不同病变长度进行分层分析。结果加宽组的1年生存率及中位生存期优于对照组（分别为81．82％比54．90％；15．20月比9．57月）。病变长度≥5cm的患者，加宽组的2年生存率优于对照组（62．50％比36．99％），统计学上有显著性差异（P＝0．048）。两组在消化道反应、骨髓抑制、放疗合并症方面无显著性差异。结论：对于病变长度≥5cm的食管癌，放疗初始野的宽度增加至7cm以上，可提高其生存率，改善疗效。
OBJECTIVE: To analyze the possibility of increasing the width of the patient to increase the efficacy of esophageal cancer radiotherapy. Methods From June 1995 to May 1997, patients with esophageal cancer who had undergone radiotherapy in our department selected 51 patients with lesion length >3cm, no surgery, radiotherapy dose ≥40Gy, and complete data. Among them, 15 cases of widening wild radiation (widening group) and 36 cases of conventional wild radiation (control group). The total dose of external irradiation was 40-75 Gy (64.31±6.70 Gy). The effects of the widening group and the control group were compared between groups and stratified by different lesion lengths. Results The 1-year survival rate and median survival of the widening group were better than those of the control group (81.82% vs. 54.90%, respectively; 15.20 months vs 9.57 months). In patients with lesion length ≥5cm, the 2-year survival rate in the widened group was better than that in the control group (62.50% vs. 36.99%), with a statistically significant difference (P=0.048). There were no significant differences between the two groups in gastrointestinal reactions, myelosuppression, and radiotherapy complications. Conclusion: For esophageal cancer with a lesion length of ≥5cm, the initial field width of radiotherapy is increased to more than 7cm, which can increase the survival rate and improve the curative effect.