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目的观察金龙胶囊联合化疗治疗晚期胃肠道肿瘤的近期疗效、毒性反应及生活质量免疫功能的变化。方法两组患者化疗方案为奥沙利铂130mg/m2d1+5-Fu500mg/m2d1-5+CF100mg/m2d1-5或是奥沙利铂130mg/m2d1+希罗达1000mg/m2bidd1~14,21天重复,应用2个周期评价。治疗组化疗开始即服用金龙胶囊,tid,连用8周,对照组单纯化疗。结果近期疗效、免疫功能治疗组明显高于对照组,毒副反应均可耐受。结论金龙胶囊联合化疗可提高患者的免疫功能,改善生活质量,且对重要器官不增加毒副作用。
Objective To observe the curative effect, toxicity and quality of life and immune function of Jinlong Capsule combined with chemotherapy in the treatment of advanced gastrointestinal cancer. Methods The chemotherapy regimen of the two groups was either oxaliplatin 130mg / m2d1 + 5-Fu500mg / m2d1-5 + CF100mg / m2d1-5 or oxaliplatin 130mg / m2d1 + Xeloda 1000mg / m2bidd1 ~ 14,21days, Apply 2 cycle evaluations. The treatment group started taking Jinlong capsule, tid, once every 8 weeks, the control group chemotherapy alone. Results of the recent treatment, immune function was significantly higher than the control group, toxic and side effects can be tolerated. Conclusion Jinlong Capsule combined with chemotherapy can improve the patient’s immune function, improve quality of life, and does not increase the toxic and side effects of vital organs.