目的:探讨全胃切除术治疗胃癌的手术适应症、手术方法及术后并发症的防治。方法:对既往本院收治77例行全胃切除术胃癌患者的临床资料进行回顾性总结分析。结果:本组70例获得随访,随访率90.9%,其中行根治性全胃切除70例,术后5年生存率为62.85%(44/70);姑息性切除4例,均于2年内死亡。本组出现吻合口瘘3例,肺部感染4例,胸腔积液7例,粘连性肠梗阻2例,倾倒综合征4例。经积极治疗均痊愈,无围术期死亡病例。结论:对于全胃切除术病例,应严格掌握临床适应证,规范手术操作,采取合适的手术方式及消化道重建方式,规范淋巴结清扫,是减少并发症、提高疗效、改善预后的重要措施。 Objective: To investigate the surgical indications, surgical methods and prevention and treatment of postoperative complications of total gastrectomy for gastric cancer. Methods: The clinical data of 77 patients who underwent total gastrectomy in our hospital were retrospectively analyzed. Results: 70 cases were followed up at 90.9%, of which 70 cases were treated by radical total gastrectomy and the 5-year survival rate was 62.85% (44/70). Palliative resection was performed in 4 cases, both of which died within 2 years . This group there were 3 cases of anastomotic leakage, 4 cases of pulmonary infection, pleural effusion in 7 cases, adhesive intestinal obstruction in 2 cases, dumping syndrome in 4 cases. After active treatment were cured, no perioperative deaths. Conclusion: For the cases of total gastrectomy, clinical indications should be strictly grasped, the operation of the operation should be strictly controlled, proper surgical methods and gastrointestinal reconstruction should be adopted to regulate the lymph node dissection, which is an important measure to reduce the complications, improve the curative effect and improve the prognosis.