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首例胰岛细胞瘤是1902年在一次尸检中偶然发现的.1927年Wilder等人报告了首例功能性胰岛细胞瘤,2年以后Graham完成了首例胰岛细胞瘤切除术.1935年Whipple成功的为一胰岛细胞瘤病人施行了首例胰腺十二指肠切除术.大多数胰岛细胞瘤可采用肿瘤摘除或胰尾切除术治疗.但是,当肿瘤位于胰头或胰腺钩突部时就应行胰十二指肠切除术.考虑到胰十二指肠切除术有较高的死亡率和并发症率,许多外科医生对此术式的应用持慎重态度.然而近年来,随着手术死亡率和并发症率的不断降低,胰十二指肠切除术已渐成为一安全的术式,其指征也较前放宽.本文报告了Johns Hopk-ins医院在过去10年中对12例胰岛细胞瘤的病人行胰十二指肠切除术的情况.资料和方法
The first case of islet cell tumor was accidentally discovered in an autopsy in 1902. Wilder et al. reported the first functional islet cell tumor in 1927, and Graham completed the first case of islet cell tumor resection two years later. In 1935 Whipple succeeded. The first case of pancreaticoduodenectomy was performed for an islet cell tumor patient. Most islet cell tumors may be treated with tumor removal or pancreatectomy. However, when the tumor is located in the head of the pancreas or the hook of the pancreas, it should be performed. Pancreatoduodenectomy. Considering the high mortality and complication rate of pancreatoduodenectomy, many surgeons are cautious about the application of this procedure. However, in recent years, with the mortality rate With the continuous reduction of complication rates, pancreaticoduodenectomy has gradually become a safe procedure, and its indications are also wider than before. This article reports 12 cases of islet cells in the past 10 years in Johns Hopk-ins Hospital. Pancreatoduodenectomy for patients with tumors. Materials and methods