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目的:观察乳舒片对乳腺增生模型豚鼠的治疗作用。方法:采用苯甲酸雌二醇联合黄体酮肌注的方法.复制豚鼠乳腺增生模型,用乳舒片治疗30 d,测定豚鼠乳头直径及高度;测定豚鼠血清雌二醇(E_2)和孕酮(P)的含量。结果:乳舒片组豚鼠乳腺高度及乳腺直径均较模型对照组明显缩小,显著降低豚鼠血清E_2和P水平。结论:乳舒片对豚鼠乳腺增生痛有较好的疗效。
Objective: To observe the therapeutic effect of Rushu Tablet on guinea pig hyperplasia model. METHODS: The guinea pig mammary gland hyperplasia model was duplicated by oestradiol benzoate combined with progesterone intramuscular injection. The diameter and height of guinea pig papillae were measured after treatment with Rushu Tablet for 30 days. Serum estradiol (E_2) and progesterone levels were measured in guinea pigs. P) content. RESULTS: The height of mammary gland and the diameter of mammary gland in guiyang mice group were significantly reduced compared with the model control group, which significantly reduced the serum E2 and P levels in guinea pigs. Conclusion: Rushu Tablet has good curative effect on guinea pig hyperplasia.