目的:探讨益肾补脾泄浊化瘀法联合羟苯磺酸钙治疗慢性肾脏病的临床疗效。方法:将30例患者随机分为治疗组和对照组。对照组口服海昆肾喜胶囊和羟苯磺酸钙,治疗组在对照组基础上加服中药汤剂治疗。结果:两组进行比较,血清肌酐、尿素氮及中医证候水平,具有显著差异(P<0.05)。结论:益肾补脾泄浊化瘀法联合羟苯磺酸钙在降低血清肌酐和尿素氮,提高肾功能水平,缓解患者临床症状方面确有良效。 Objective: To investigate the clinical efficacy of Yishen Bu Bu Xie Xie Huayu method combined with calcium dobesilate in the treatment of chronic kidney disease. Methods: Thirty patients were randomly divided into treatment group and control group. The control group was orally administered with Hai Kun Shen Xi Capsule and calcium dobesilate, and the treatment group was treated with Chinese herbal decoction on the basis of the control group. Results: There was significant difference between the two groups in serum creatinine, blood urea nitrogen and TCM syndromes (P <0.05). Conclusion: Yishen Buwei Xiezhuyu Decoction combined with calcium dobesilate has good effect in lowering serum creatinine and urea nitrogen, improving renal function and alleviating the clinical symptoms of patients.