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654-2是人工合成的山茛菪碱,为胆碱能神经阻滞药,具有扩张微小动脉,改善微循环的良好作用。国内资料指出,用于治疗急性肾炎合并心力衰竭,高血压脑病及肺部改变,可以取得较好的效果。为了进一步证实本药对急性肾炎的作用,在1973年内,我们曾用北京制药厂生产的654-2注射药,治疗小儿急性肾炎80例(以下称治疗组),并与同期住院的40倒对照(以下称对照组),通过临床观察,初步认为本药治疗小儿急性肾炎具有一定的优点,现将结果报告如下:
654-2 is a synthetic anisodamine, a cholinergic nerve blocker, with the expansion of small arteries, to improve the good role of microcirculation. Domestic data pointed out that for the treatment of acute nephritis with heart failure, hypertensive encephalopathy and lung changes, can achieve better results. In order to further confirm the effect of this medicine on acute nephritis, in 1973, we used 654-2 injection manufactured by Beijing Pharmaceutical Factory to treat 80 children with acute nephritis (hereinafter referred to as the treatment group) and compared with 40 inpatients (Hereinafter referred to as the control group), through clinical observation, initially that the drug treatment of children with acute nephritis has some advantages, the results are reported as follows: