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目的:探讨铝碳酸镁联合吗丁啉治疗功能性消化不良的临床效果。方法:选取2010年11月～2011年11月期间在我院接受治疗的功能性消化不良患者78例,将其随机分为对照组和研究组,各39例。对照组给予吗丁啉进行治疗。研究组采用吗丁啉与铝碳酸镁进行联合治疗。结果:治疗后,对照组总有效率为58.97%,研究组总有效率为92.31%,两组总有效率比较,差异显著,具有统计学意义(P<0.05)。对照组不良反应发生率为17.95%,研究组不良反应发生率为20.51%。两组不良反应发生率比较,无显著性差异,不具有统计学意义(P>0.05)。讨论:采用铝碳酸镁与吗丁啉联合治疗功能性消化不良,具良好的协同作用,能有效缓解患者的相关症状,且无明显不良反应发生,具有临床推广价值。
Objective: To investigate the clinical efficacy of magnesium carbonate combined with domperidone in the treatment of functional dyspepsia. Methods: Seventy-eight patients with functional dyspepsia treated in our hospital from November 2010 to November 2011 were randomly divided into control group and study group, with 39 cases in each group. The control group was given morphine for treatment. Study group using domperidone and aluminum magnesium carbonate combination therapy. Results: After treatment, the total effective rate was 58.97% in the control group and 92.31% in the study group. There was significant difference between the two groups in total effective rate (P <0.05). The incidence of adverse reactions in the control group was 17.95%, and the incidence of adverse reactions in the study group was 20.51%. There was no significant difference between the two groups in the incidence of adverse reactions, with no statistical significance (P> 0.05). DISCUSSION: The combination of aluminum magnesium carbonate and domperidone for functional dyspepsia has good synergistic effect and can effectively relieve the symptoms of patients with no obvious adverse reactions and has clinical popularization value.