目的 :探讨不良孕产与染色体异常的关系。方法 :对宁夏地区 134 4例因不良孕产史而行咨询者 ,取其外周血 ,常规培养、制片、G显带 ,进行染色体核型分析。结果 :染色体核型正常 130 3人 ,占 96 95% ;核型异常 4 1人 ,占 3 0 5%。结论 :不良孕产与染色体异常有关 ,染色体异常是导致不良孕产史的重要细胞遗传因素。在不良孕产史夫妇中进行细胞遗传学检查对于明确病因、生育指导以及提高我国人口素质都具有重要意义 Objective: To explore the relationship between poor pregnancy and chromosomal abnormalities. Methods: A total of 134 4 cases of unwanted pregnancy in Ningxia were enrolled in this study. Peripheral blood, routine culture, preparation and G - banding were used to analyze the karyotype. Results: There were 1303 normal karyotypes, accounting for 96.95%; 4 karyotype abnormalities, accounting for 30.5%. Conclusion: Adverse pregnancy is related to chromosomal abnormalities. Chromosome abnormality is an important cytogenetic factor leading to poor pregnancy history. Cytogenetic tests in poor couples of maternal history are important for clarifying causes, giving birth guidance, and improving the quality of our population.