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例1女,22岁,会阴部反复溃疡伴渗出液2月余,慢性贫血病容,面部可见散在分布疱疹,口唇黏膜破溃,双侧颈部可触及一肿大淋巴结。例2男,46岁,全身酸痛,乏力不适,后逐渐出现发热,T 39℃以上,前胸部可见散在分布皮下瘀点,右侧胸锁乳突肌后缘可触及数枚肿大淋巴结。例3女,40岁,无明显诱因出现发热,伴畏寒、寒颤,全身乏力、肌肉酸痛,四肢偶见瘀斑,脸部见散在分布红色皮疹,浅表淋巴结未触及肿大。3例均有发热、贫血、皮疹或溃疡、脾大等。实验室检查示外周血均呈三系减少,肝功:AST和(或)ALT升高,HIV抗体(+),血培养见马尔尼菲青霉菌等特征。均诊断为艾滋病并发马尔尼菲青霉菌感染。
Case 1 female, 22 years old, perineal ulcer with exudate over and over for more than 2 months, chronic anemia, facial scattered scattered herpes, lip mucosa ulceration, both sides of the neck can reach a swollen lymph nodes. Case 2 male, 46 years old, body aches, weakness and discomfort, and then gradually fever, T 39 ℃ above the anterior chest visible scattered subcutaneous petechiae, the right sternocleidomastoid muscle posterior edge can touch several enlarged lymph nodes. Example 3 female, 40 years old, no obvious incentive to cause fever, with chills, chills, malaise, muscle soreness, occasional ecchymosis in the limbs, face scattered scattered red rash, superficial lymph nodes did not touch the swollen. 3 cases were fever, anemia, rash or ulcers, splenomegaly and so on. Laboratory tests showed that peripheral blood showed three lines decreased, liver function: AST and (or) ALT increased, HIV antibody (+), blood culture, see Penicillium marneffei and other characteristics. All were diagnosed with AIDS and Penicillium marneffei infection.