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目的:探讨卵冠丘复合体中的血凝块对IVF-ET的影响。方法:采用IVF-ET常规长方案超促排卵、获得的卵冠丘复合体上有血凝块的患者为研究对象,将其随机分为A组,切除血凝块,50例;B组,不切除,53例;另以获得的卵丘复合体上无血凝块者为对照组(C组,91例);比较分析各组的临床结局。结果:3组患者的年龄、不孕年限、Gn用量、Gn使用总天数及获卵数组间两两比较,均无统计学差异,A组的受精率及2PN率最高,为85.4%和71.1%,C组次之,为77.5%和64.9%,B组最低,为75.8%和62.2%,A组显著高于B、C组(P<0.01),B、C组间统计学差异;移植后A组的种植率、妊娠率略高于B、C组,但无统计学差异(P>0.05)。结论:切除卵冠丘复合体上的血块不会增加操作成本及操作的复杂性,但却可以近一步改善患者的助孕结局,值得推广使用。
OBJECTIVE: To investigate the effect of blood clots in the compound corpus luteum on IVF-ET. Methods: The IVF-ET routine long-term ovulation induction ovulation, obtained on the corpus cap complex cuff patients were studied, were randomly divided into A group, resection of blood clots, 50 cases; B group, Without resection, 53 cases; the other obtained cumulus complex without blood clots as a control group (C group, 91 cases); comparative analysis of the clinical outcomes of each group. Results: There was no significant difference in the age, the duration of infertility, the amount of Gn, the total number of Gn days and the number of oocytes retrieved in each group. The fertilization rate and 2PN rate in group A were the highest (85.4% vs 71.1% , The lowest in group B was 75.8% and 62.2%, the lowest in group B was significantly higher than that in group B and C (P <0.01), the difference was statistically significant between group B and C Group A implantation rate, pregnancy rate slightly higher than the B, C group, but no significant difference (P> 0.05). Conclusion: The removal of blood clots on the coronoid complex will not increase the operating costs and the complexity of the operation, but it can further improve the outcome of patients with pregnancy, which is worth promoting.