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本文采用观察同一个体多种指标的方法,研究国产云芝胞内多糖对C57BL/6J/J小鼠体内的黑色素瘤B16的抗瘤作用及其促进荷瘤鼠抗肿瘤免疫反应的作用.结果表明,这种云芝多糖对黑色素瘤B16的抑瘤率为40.8%,与环磷酰胺合用对黑色素瘤B16人工肺转移的抑制率达84.4%;其抗瘤作用机理以拮抗肿瘤的免疫抑制作用,多方面有效地促进行瘤鼠的非特异性抗肿瘤免疫反应为主,对正常机体的免疫反应也有一定促进作用.
In this paper, we observed the anti-tumor effect of domestic polysaccharides of Cortex Coriolus versicolor on the melanoma B16 in C57BL / 6J / J mice and its anti-tumor immune response to tumor-bearing mice . The inhibition rate of the polysaccharide of PSK to B16 of melanoma was 40.8%, and the inhibition rate of cyclophosphamide combined with cyclophosphamide to the B16 artificial lung metastasis was 84.4%. Its anti-tumor mechanism was antagonistic to tumor immunosuppression, Promote the non-specific anti-tumor immune response of tumor-bearing mice in various aspects and effectively promote the immune response of normal body.