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目的研究老年反流性食管炎患者焦虑和抑郁心理状态及黛力新的治疗效果。方法选取我院从2014年7月至2015年12月收治的老年反流性食管炎伴焦虑抑郁患者100例,按照随机数字表法将100例老年反流性食管炎伴焦虑抑郁患者分为观察组(50例)和对照组(50例);对照组采取常规治疗,观察组在对照组的基础上合并黛力新治疗。将两组患者的汉密尔顿焦虑量表(HAMA)评分与汉密尔顿抑郁量表(HAMD)评分、反流性食管炎症状程度积分(GERDQ)数值以及临床有效率进行对比分析。结果两组患者治疗前HAMA、HAMD和GERDQ评分,组间无明显差异(P>0.05)。治疗后两组患者的HAMA、HAMD和GERDQ评分均降低(P<0.05),且观察组上述量表评分低于对照组,两组比较差异具有统计学意义(P<0.05);观察组的临床有效率(96.00%)显著高于对照组的临床有效率(82.00%),差异具有统计学意义(P<0.05)。结论黛力新辅助治疗老年返流性食管炎伴焦虑抑郁症状的患者,可显著减轻患者的焦虑抑郁症状,改善患者的临床效果,因此值得在临床推广应用。
Objective To study the psychological status of anxiety and depression in elderly patients with reflux esophagitis and the efficacy of Deanxit. Methods A total of 100 elderly patients with reflux esophagitis and anxiety and depression who were treated in our hospital from July 2014 to December 2015 were enrolled. According to the random number table, 100 elderly patients with reflux esophagitis and anxiety and depression were divided into observation (50 cases) and control group (50 cases). The control group was treated with routine treatment. The observation group was treated with dextrose on the basis of the control group. The Hamilton Anxiety Scale (HAMA) score was compared with the Hamilton Depression Rating Scale (HAMD) score, Reflux Esophagitis Symptom Integral Score (GERDQ) score, and clinical response rate in both groups. Results There was no significant difference in HAMA, HAMD and GERDQ scores between the two groups before treatment (P> 0.05). The scores of HAMA, HAMD and GERDQ in the two groups were decreased after treatment (P <0.05), and the scores of the above scales in the observation group were lower than those in the control group, with statistical significance (P <0.05) The effective rate (96.00%) was significantly higher than that of the control group (82.00%), the difference was statistically significant (P <0.05). Conclusion Deanxit adjuvant treatment of senile reflux esophagitis with symptoms of anxiety and depression in patients with anxiety and depression symptoms can be significantly reduced and improve the clinical effect of patients, it is worth in the clinical application.