七十年代初期开始用干扰素治疗人的恶性肿瘤,至今已有十余年的历史。但由于受产量的限制,一直未能扩大临床实验范围。进入八十年代,由于新技术的发展,采用重组基因法已能大量生产,因此目前世界各国都在积极开展研究各种干扰素。本文拟就干扰素治疗恶性肿瘤的临床效果,加以综述。 Since the early 1970s, interferon has been used to treat human malignant tumors for more than ten years. However, due to the limited production, it has been unable to expand the scope of clinical trials. Since the 1980s, due to the development of new technologies, the recombinant gene method has been able to mass-produce it. Therefore, various countries in the world are actively studying various kinds of interferons. This article intends to interferon treatment of malignant tumors clinical effects, to be reviewed.