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目的进一步提高对恶性血液病合并真菌感染的认识,改进治疗措施,减少真菌感染率、死亡率,提高生存率。方法分析住院的恶性血液病合并真菌感染患者30例的一般临床资料、微生物学检查及治疗情况。结果真菌感染的发病率不断增高,病原菌以念珠菌为主,30例患者应用抗真菌药物后总有效率为61%,死亡率为40%。结论真菌感染是恶性血液病患者化疗期间严重的并发症和主要的死亡原因之一,早期诊断及经验治疗具有重要意义。
Objective To further improve awareness of malignant hematological diseases complicated with fungal infections, improve treatment measures, reduce fungal infection rate, mortality and increase survival rate. Methods The clinical data, microbiological examination and treatment of 30 patients with malignant hematological diseases complicated with fungal infection in hospital were analyzed. Results The incidence of fungal infections was continuously increased. The pathogen was mainly Candida albicans. The total effective rate was 61% and the mortality rate was 40% after antifungal treatment in 30 patients. Conclusion Fungal infection is one of the major causes of death and complications during the chemotherapy of patients with hematologic malignancies. Early diagnosis and experience treatment are of great significance.