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本文报告4例绿脓杆菌败血症,皮肤上均有坏疽性臁疮损害,男女各半,年龄6月～1岁,其中2例死亡。作者在讨论中提到暴发型绿脓杆菌败血症可有革兰氏阴性杆菌引起的休克症状:低温、低血压、心动过速、无尿、麻痹性肠梗阻和白细胞减少。引起此作用的内毒素是细菌细胞壁中的蛋白脂多糖复合物。可发生肝细胞损伤,导致黄疸,结合和未结合的胆红素均增高。在体表感染时,可分离出3种外毒素:1.多种细胞毒素性酶通过直接作用和血管血栓形成导致肉芽组织的局灶性坏死和边缘性坏疽性脓皮病
This article reports 4 cases of Pseudomonas aeruginosa sepsis, gangrenous scabies are on the skin damage, men and women in each half, aged 6 months to 1 year of age, of which 2 were killed. The authors mentioned in the discussion that fulminant bacteremia may be caused by Gram-negative bacilli: hypothermia, hypotension, tachycardia, anuria, paralytic ileus and leukopenia. The endotoxin that causes this effect is a proteoglycan complex in the bacterial cell wall. Hepatocyte damage can occur, leading to jaundice, both increased and unbound bilirubin. In the body surface infection, three kinds of exotoxins can be isolated: 1. A variety of cytotoxic enzymes lead to focal necrosis of granulation tissue and marginal gangrenous pyoderma through direct action and vascular thrombosis