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由于人口的老龄化,老年患者用药机会增多,随之而来的药物不良反应也在增加。发生不良反应原因较多,其中由于药动学的改变所带来的问题是主要因素之一。因此应充分了解老年人药动学特点,使药物发挥最佳效果,同时将药物不良反应控制在最小程度。
Due to the aging of the population, the opportunities for the elderly to use drugs increased, followed by adverse drug reactions are also increasing. There are many reasons for adverse reactions, of which the problems caused by the change of pharmacokinetics are one of the main factors. Therefore, we should fully understand the characteristics of pharmacokinetics in the elderly, so that the best drug effects, while adverse drug reactions to a minimum.