Anti-inflammatory effects of Morninga oleifera lam extract in rats

来源 :Asian Pacific Journal of Tropical Medicine | 被引量 : 0次 | 上传用户:charles_y_tang
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Objective:To investigate the acute and delayed anti-inflammatory effects of Morning oleifera lam(MOL) crude methanolic extract.Methods:Compared the anti-inflammatory effects of MOL with that of standard anti-inflammatory agents like indomethacin and hydrocortisone using Air Pouch Model.Results:In both acute and delayed inflammation,the MOL extract produced dose dependent anti-inflammatory effect[acute IC_(50)=(399.30±5.43) mg/kg;delayed IC_(50)=(510.26±4.53) mg/kg].The order of anti-inflammatory potency for the three drugs was hydrocortisone> indomethacin > MOL.Conclusions:These observations indicate that MOL possesses potential anti-inflammatory property. Objective: To investigate the acute and delayed anti-inflammatory effects of Morning oleifera lam (MOL) crude methanolic extract. Methods: Compared the anti-inflammatory effects of MOL with that of standard anti-inflammatory agents like indomethacin and hydrocortisone using Air Pouch Model. Results: In both acute and delayed inflammation, the MOL extract produced dose dependent anti-inflammatory effect [acute IC 50 = (399.30 ± 5.43) mg / kg; delayed IC 50 = (510.26 ± 4.53) mg / kg] The order of anti-inflammatory potency for the three drugs was hydrocortisone> indomethacin> MOL.Conclusions: These anomalies that MOL possesses potential anti-inflammatory property.
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