肿瘤可以在原位生长或直接浸润周围组织引起局部的出血,坏死、梗阻、肿块等症状和体征,也可以向远隔器官转移或通过一些中介物质间接作用于远隔器官甚至全身各系统、产生一系列的临床表现,后者即称为伴癌综合征。有人统计全部肿瘤病人的15～20％和晚期难治性肿瘤的75％在一生中至少出现一种伴癌综合征。这些症候群可以在肿瘤晚期广泛转移时出现,亦可发生于肿瘤的亚临床期,因此,这些综合征既是早期肿瘤的信号,也是肿瘤复发和转移的标志。文献中报道前列腺癌(Pca)伴癌综合征涉及全身多系统多器官,临床表现变化多端,本文拟对此作一综述。 Tumor can grow in situ or directly infiltrate the surrounding tissue to cause local bleeding, symptoms and signs such as necrosis, obstruction, and lump. It can also be transferred to distant organs or indirectly through distant organs or even systemic systems through some intermediary substances. A series of clinical manifestations, the latter is known as the companion cancer syndrome. It was reported that 15 to 20% of all cancer patients and 75% of advanced refractory tumors had at least one associated cancer syndrome in their lifetime. These syndromes can occur during the extensive metastasis of advanced tumors, but also in the subclinical phase of the tumor. Therefore, these syndromes are both signals of early tumors, and also a sign of tumor recurrence and metastasis. The literature reports that prostate cancer (Pca) associated with cancer syndrome involves systemic multiple systems and multiple organs, and its clinical manifestations are varied. This article is intended to review it.