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采用ＣＯＸ回归模型对影响小肝癌切除术后复发的２５项因素进行了分析，在ＣＯＸ模型分析中，影响复发的显著因素依次为肿瘤包膜、术后ＡＦＰ变化、癌周淋巴细胞量、手术方式和切缘至肿瘤距离。本组１、３、５年累计复发率分别为３０．５％，４４．４％和５１．４％。结果提示，术后３年内为复发高危期，出现肿瘤包膜和癌周淋巴细胞数量增加对复发具有抑制作用。首次手术采用根治性切除的术式，切缘至肿瘤的距离≥２ｃｍ，使术后ＡＦＰ降至正常，可明显地减少复发。
The COX regression model was used to analyze the 25 factors affecting the recurrence of small hepatocellular carcinoma after resection. In the COX model analysis, the significant factors affecting recurrence were tumor capsule, postoperative AFP change, pericancerous lymphocyte volume, and surgical methods. Distance from the margin to the tumor. The cumulative recurrence rates in the 1, 3, and 5 years were 30.5%, 44.4%, and 51.4%, respectively. The results suggest that high risk of recurrence occurs within 3 years after surgery, and the increase in the number of tumor capsules and lymphocytes around the tumor suppresses recurrence. For the first operation, radical resection was performed. The distance from the margin to the tumor was ≥2cm, which reduced the postoperative AFP to normal and significantly reduced the recurrence.