药物过敏性休克(以下简称药敏休克)是临床上经常遇到的意外急症。本文就发病机理、临床表现、预防方法及治疗措施作一简要介绍,以供临床参考。发病机理药敏休克是由具有抗原性的药物引起的一种全身性、速发型的严重变态反应。这些药物可以是完全抗原,如血清制剂(破伤风抗毒素、白喉抗毒素等);也可以是半抗原(如青霉素、磺胺、奎宁、非那西汀、安替匹林等)低分子化学物质。半抗原与人体组织蛋白结合后,可构成完全抗原。当具有过敏性体质的机 Drug allergic shock (hereinafter referred to as drug-induced shock) is clinically often encountered accidental emergency. This article on the pathogenesis, clinical manifestations, prevention methods and treatment measures for a brief introduction for clinical reference. Pathogenesis Drug-induced shock is caused by a drug with antigenic systemic, rapid-onset severe allergic reaction. These drugs can be complete antigens, such as serum preparations (tetanus antitoxin, diphtheria anti-toxin, etc.); also be a hapten (such as penicillin, sulfonamides, quinine, phenacetin, antipyretics, etc.) low molecular weight chemicals. Hapten and human tissue protein binding, can constitute a complete antigen. When the machine with an allergic constitution