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目的：评价１％ 盐酸特比萘芬乳膏治疗皮肤浅部真菌病的临床疗效和安全性。方法：采用随机双盲、有效对照、平行分组试验，与进口的同类药物疗霉舒霜进行疗效和安全性比较。观察了可供疗效评价的７０ 例体股癣和花斑癣患者，其中试验组３５ 例，对照组３５ 例。结果：总治愈率９７－１４％ （ 对照组９７－１４％ ），总有效率１００－０％ （对照组９７－１４％） ，总真菌清除率１００－０％ （对照组９７－１４％ ）。不良反应发生率０（ 对照组２－７８％） 。两者的临床治愈率、有效率和真菌清除率及不良反应发生率差异均无显著性。结论：１％ 盐酸特比萘芬乳膏治疗皮肤浅部真菌病疗效确切，安全性好。
Objective: To evaluate the clinical efficacy and safety of 1% terbinafine hydrochloride cream in the treatment of superficial mycosis of the skin. Methods: Randomized double-blind, effective control, parallel group test, and similar imported drugs Shu Shuang Shuang efficacy and safety comparison. 70 patients with tinea corporis and tinea versicolor who were evaluated for efficacy were observed, of which 35 were in the test group and 35 in the control group. Results: The total cure rate was 97-14% (control group 97-14%), the total effective rate was 100-0% (control group 97-14%), the total fungal clearance rate was 100-0% (control group 97-14%) . The incidence of adverse reactions 0 (control group 2-78%). There was no significant difference between the two groups in the clinical cure rate, effective rate, fungal clearance and the incidence of adverse reactions. Conclusion: 1% Terbinafine hydrochloride cream for the treatment of superficial mycosis of the skin is effective and safe.