盘状红斑狼疮(DLE)是一种累及粘膜和皮肤的结缔组织病。大约有1.3%-6.51%的DLE患者可发展为系统性红斑狼疮(SLE)。DLE的口腔损害大多见于下唇唇红,其次是颊、舌等部位。在临床上单发于唇部的DLE与慢性唇炎相混淆,面颊部的DLE与扁平苔藓(LP)也难以鉴别。根据上述情况,本文对我科自1976年以来临床上诊断为DLE的病例作了分析,试图有助于早期作出鉴别诊断。 Discoid lupus erythematosus (DLE) is a connective tissue disease that affects the mucous membranes and the skin. About 1.3%-6.51% of patients with DLE develop systemic lupus erythematosus (SLE). The oral lesions of DLE are mostly found in the lower lip and lip, followed by the cheeks and tongue. In the clinic, DLE on the lip is confused with chronic cheilitis, and DLE on the cheek and lichen planus (LP) are difficult to distinguish. Based on the above situation, this article analyzed the cases of clinical diagnosis of DLE in our department since 1976, trying to help make early differential diagnosis.