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拉莫三嗪为苯三嗪类抗癫痫药,具有广谱、安全、高效的特点,对多种癫痫发作和癫痫综合征均有良好疗效。近年来国内有文献报道其不良反应,现概述如下:1多形红斑型药疹白书仙报道,患女,50岁,因癫痫给予拉莫三嗪治疗,服药1月后出现口腔溃疡,颈周起红疹,色鲜红,表现多样,多数呈虹膜样表现,部分呈粟米大小丘疹、丘疱疹,皮损累及口腔、眼、外生殖器等粘膜,伴高热,停药后予抗过敏对症治疗,9天后病情
Lamotrigine is a benzotriazine antiepileptic drug which has the characteristics of broad spectrum, safety and high efficiency, and has good curative effect on various epileptic seizures and epilepsy syndromes. In recent years, there are reports of adverse reactions in the domestic literature, are summarized as follows: 1 polymorphic erythema-type drug rash Bai Shuxian reported that suffering from women, 50 years old, given lamotrigine for epilepsy treatment, oral ulcers after taking medicine in January, Color bright red, the performance is varied, the majority of showed iris-like performance, part was corn size papules, herpes zoster, skin lesions involving the oral cavity, eyes, external genital mucosa, with fever, anti-allergic symptomatic treatment after withdrawal, 9 days after the disease