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卵巢癌是妇产科病死率最高的恶性肿瘤,临床上多采用手术切除和联合化疗等方法治疗,效果有限。近年来,多药耐药相关基因及耐药相关蛋白等的发现揭示了卵巢癌耐药机制,现就有关现状及进展作一综述。
Ovarian cancer is the highest mortality of obstetrics and gynecology malignant tumors, the clinical use of surgical resection combined with chemotherapy and other methods, the effect is limited. In recent years, the discovery of multidrug resistance-related genes and drug-resistance-related proteins revealed the mechanism of drug resistance in ovarian cancer. Present status and progress are summarized.