22例老年NIDDM患者和18例正常人检测结果显示,老年NIDDM的LPO显著升高,SOD、CAT、GSH-Px、Se-GSH-Px显著降低,LPO与上述四种抗氧化酶负相关;BG、TG、TC、LDL和ApoB显著升高,HDL显著降低;SOD与BG负相关;LPO与TG、TC、LDL正相关,与HDL、ApoA_1负相关。提示老年NIDDM患者LPO升高可能与其溏、脂代谢紊乱有关。LPO的持续升高可能是其心血管并发症发生的重要因素之一。 The results of 22 elderly NIDDM patients and 18 normal subjects showed that the LPO of elderly NIDDM patients were significantly increased, while the levels of SOD, CAT, GSH-Px and Se-GSH-Px were significantly decreased, while LPO was negatively correlated with the above four anti-oxidative enzymes; , TG, TC, LDL and ApoB were significantly increased, HDL was significantly decreased; SOD was negatively correlated with BG; LPO was positively correlated with TG, TC, LDL and negatively correlated with HDL, ApoA_1. Tip elderly patients with NIDDM increased LPO may be related to their fat, lipid metabolism disorders. The continuous increase of LPO may be one of the important factors of its cardiovascular complications.