目的研究抗支颗粒治疗肺炎支原体感染患儿的临床疗效及不良反应。方法收集入住我院的肺炎支原体感染患儿180例,分为实验组120例和对照组60例,实验组给予抗支颗粒治疗,对照组给予阿奇霉素治疗,治疗2周。观察并比较两组的临床疗效及不良反应。结果实验组和对照组治疗有效率均为96.67%,两组之间有效率无统计学意义(P>0.05);实验组在咳嗽、咯痰消失时间方面显著短于对照组,比较有显著性差异(P<0.05);实验组不良反应发生率明显少于对照组(P<0.05)。结论抗支颗粒治疗肺炎支原体感染患儿的临床疗效与阿奇霉素的疗效相当,但无明显不良反应,可以作为优选的治疗方案。 Objective To study the clinical efficacy and adverse reactions of Kangzhipian Granules in the treatment of Mycoplasma pneumoniae infection in children. Methods 180 cases of Mycoplasma pneumoniae infection in our hospital were collected and divided into experimental group (120 cases) and control group (60 cases). The experimental group was treated with Kangzi Granule, while the control group was treated with azithromycin for 2 weeks. Observed and compared the clinical efficacy and adverse reactions in both groups. Results The effective rate of both experimental group and control group was 96.67%, there was no significant difference between the two groups (P> 0.05); the experimental group was significantly shorter than the control group in the time of disappearance of cough and expectoration (P <0.05). The incidence of adverse reactions in the experimental group was significantly less than that in the control group (P <0.05). Conclusion The clinical curative effect of Kangzhi granule in treating children with mycoplasma pneumoniae infection is similar to that of azithromycin, but no obvious adverse reactions, which can be used as the preferred treatment plan.