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目的研究弱视儿童瞬态图形视觉诱发电位(pattern visual evoked potential,PVEP)视力与国际标准视力表视力之间的相关性,探讨用视觉诱发电位技术检测弱视儿童客观视力的可行性及临床实用性。方法检测32例(64眼)3～11岁的弱视患儿的瞬态图形视觉诱发电位视力(PVEP视力)及国际标准视力表视力并进行相关分析。PVEP检测使用美国LKC公司生产的UTAS-E3000电生理诊断系统,使用5个不同空间频率的水平条栅作为刺激,时间频率为2Hz,将能够观察到典型PVEP波形的最高空间频率作为患儿的PVEP视力。结果瞬态图形视觉诱发电位视力与国际标准视力表视力之间有良好的相关性(r=0.712,P<0.05);弱视程度不同,瞬态图形视觉诱发电位视力的分布亦有显著差异;国际标准视力表视力与瞬态图形视觉诱发电位视力存在一定数值对应规律。重度弱视组,PVEP视力100%在0.85cpd(最低空间频率);中度弱视组,PVEP视力分布相对较分散,集中分布在3.40cpd和6.80cpd,无1眼达13.60cpd;轻度弱视组,PVEP视力集中分布在3.40cpd和6.80cpd两个空间频率,其中达6.80cpd者占71.2%;视力≥0.9组,全部PVEP视力≥6.80cpd。四组PVEP视力呈相对集中分布,随国际标准视力提高,PVEP视力也相应提高。结论在无法使用国际标准视力表检查弱视儿童视力时,可以运用瞬态图形视觉诱发电位技术进行客观视力评估,尤其是低龄弱视儿童。
Objective To study the correlation between visual evoked potentials (PVEP) of visual acuity visual acuity and visual acuity (WHA) in amblyopic children and to explore the feasibility and clinical utility of visual evoked potentials (PSV) in detecting visual acuity in amblyopic children. Methods 32 patients (64 eyes) with visual acuity visual acuity (PVEP) and visual acuity (RMS) visual acuity visual acuity visual acuity visual acuity visual acuity visual acuity of children aged 3-11 years old were detected and analyzed. The PVEP test uses the UTAS-E3000 electrophysiological diagnostic system manufactured by LKC, USA, using 5 horizontal bars of different spatial frequencies as stimuli at a time frequency of 2 Hz, and will be able to observe the highest spatial frequency of a typical PVEP waveform as the PVEP vision. Results There was a good correlation between transient visual acuity visual acuity and visual acuity of the international standard visual acuity (r = 0.712, P <0.05). There was also a significant difference in visual acuity distribution of transient visual evoked potential Standard vision chart visual acuity and transient visual acuity potential visual acuity there is a certain value corresponding to the law. Severe amblyopic group, PVEP visual acuity of 100% at 0.85cpd (lowest spatial frequency); moderate amblyopia group, PVEP visual acuity distribution is relatively dispersed, concentrated in 3.40cpd and 6.80cpd, no 1 eye up to 13.60cpd; mild amblyopia group, PVEP eyesight focused on two spatial frequencies of 3.40 cpd and 6.80 cpd, of which 71.80 cpd accounted for 71.2%; visual acuity ≥ 0.9 group, all PVEP visual acuity ≥ 6.80 cpd. The four groups of PVEP eyesight was relatively concentrated distribution, with the international standard of vision improved PVEP visual acuity also increased accordingly. Conclusions In the case of visually impaired children with vision amblyopia can not be used to detect visual acuity, visual acuity potential can be used for transient visual assessment of visual acuity, especially in young children with amblyopia.