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目的探讨~(18)F-FDG PET/CT对儿童神经母细胞瘤(neuroblastoma,NB)近期疗效评估的应用价值。方法回顾性分析我院2012-04至2015-04收治的14例行~(18)F-FDG PET/CT检查的NB患儿临床资料,观察~(18)F-FDG PET/CT对NB患儿疗效的评估及对复发、转移病灶的检出情况。结果 14例NB患儿共行18例次~(18)F-FDG PET/CT检查,其中8例次显示不同程度、不同部位的FDG异常摄取增高灶,指导临床及时调整了治疗。~(18)F-FDG PET/CT改变了1例患儿分期,由初始Ⅳs期提高至Ⅳ期。4例复发患儿共17处病灶,~(18)F-FDG PET/CT对复发、转移病灶的检出率为88.2%(15/17),遗漏1处颅内微小转移灶和1例骨髓微小转移。结论~(18)F-FDG PET/CT对儿童NB近期疗效的评估具有重要价值,可作为NB患儿随访的辅助检查之一。
Objective To investigate the value of ~ (18) F-FDG PET / CT in evaluating the short-term curative effect of neuroblastoma (NB) in children. Methods The clinical data of 14 children with NB-18 F-FDG PET / CT admitted to our hospital from April 2012 to April 2015 were analyzed retrospectively. The effect of ~ (18) F-FDG PET / Evaluation of the efficacy of children and detection of recurrent and metastatic lesions. Results Fourteen cases of NB children underwent 18 ~ (18) F-FDG PET / CT examinations. Among them, 8 cases showed different degrees of abnormal FDG uptake at different sites, which guided clinical treatment timely. ~ (18) F-FDG PET / CT changed the stage of one patient, from the initial Ⅳs to Ⅳ. There were 17 lesions in 4 recurrent children, 88.2% (15/17) in ~ (18) F-FDG PET / CT and 1 missed intracranial micrometastasis and 1 bone marrow Micro transfer. Conclusions ~ (18) F-FDG PET / CT is of great value in assessing the short-term effect of NB in children and can be used as one of the auxiliary examinations for follow-up of children with NB.