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IgE 合成的调节是一个复杂的过程,它既包括细胞间,也包括分子间的相互作用。人体 B-细胞中IgE 合成的诱导被认为是所谓的二个信号的模式。第一信号由细胞因子 IL-4或 IL-13介导。IL-4和 IL-13主要由 T-细胞产生,也可由肥大细胞和嗜碱性细
The regulation of IgE synthesis is a complex process that involves both intercellular and intermolecular interactions. The induction of IgE synthesis in human B-cells is thought to be a mode of the so-called two signals. The first signal is mediated by the cytokines IL-4 or IL-13. IL-4 and IL-13 are mainly produced by T-cells, but also by mast cells and basophils