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新合成的噻唑类 Schiff碱 N-( 2 -四氢苯并噻唑 ) -2 -羟基苯甲亚胺及类似化合物与 Ce4 +反应可产生微弱的化学发光 ,使用增敏剂奎宁可使发光显著增强 .研究其发光反应动力学曲线、荧光光谱、化学发光光谱以及 Schiff碱与 Ce4 +混合前后紫外可见吸收光谱的变化 ,确定了发生反应的官能团 ,讨论了发光反应的机理 .考察了奎宁存在下 Schiff碱与 Ce4 +化学发光反应条件及共存物质对发光强度的影响 ,建立了流动注射化学发光测定 Schiff碱的方法 .该法线性范围为 2 .0× 1 0 -7～ 1 .0× 1 0 -4 mol/ L,检出限为 8.0× 1 0 -8mol/ L,对 2 .0× 1 0 -6mol/ L噻唑类 Schiff碱 7次平行测定的相对标准偏差为 2 .4 % .除 Mn2 +,Fe3 +,Fe2 +,Bi3 +,Ti+外 ,大部分金属离子及 50 0倍药物辅料淀粉不干扰噻唑类 Schiff碱测定 .与已有方法相比 ,具有灵敏、快速、简单、全自动等特点 ,成功地用于合成样品的分析
The newly synthesized thiazole Schiff base N- (2 - tetrahydrobenzothiazole) -2 - hydroxybenzimine and similar compounds reacted with Ce4 + to produce weak chemiluminescence. The use of quinine as sensitizer enhanced the luminescence significantly The changes of kinetic curves, fluorescence spectra, chemiluminescence spectra and UV-Vis absorption spectra of Schiff base and Ce4 + before and after the reaction were studied, and the functional groups were determined and the mechanism of luminescence reaction was discussed. Schiff base and Ce4 + chemiluminescence reaction conditions and the coexistence of substances on the luminous intensity, flow injection chemiluminescence determination of Schiff base method. The linear range of the law is 2.0 × 10 -7 ~ 1 .0 × 10 The detection limit was 8.0 × 10 -8 mol / L, and the relative standard deviation (RSD) of 7 times parallel determination of 2.0 × 10 -6 mol / L thiazole Schiff base was 2.4% +, Fe3 +, Fe2 +, Bi3 +, Ti +, most of the metal ions and 50 times the drug excipient starch do not interfere with the determination of thiazole Schiff base. Compared with the existing methods, with sensitive, fast, simple, fully automatic Features that have been successfully used for the analysis of synthetic samples