慢性化脓性中耳炎对感受器有一定影响。以前的实验研究曾发现化脓性中耳炎的耳蜗和前庭感受器的超微结构都有改变。认为是由于中耳与内耳间的血管连系,或是毒素经迷路两窗进入内耳所致。本文用两组实验动物在慢性化脓性中耳炎的条件下观察声音如何影响耳蜗与前庭感受器。试验组(3只兔和4只豚鼠),对照组(3只兔和3只豚鼠),都将一侧鼓膜穿孔感染金黄色葡萄球菌,造成慢性化脓性中耳炎。试验组动物用4KHz、100dB的声音刺激6小时,每日一次共五次。观察6个月,瞬间断头打开鼓室除去脓性分泌物,见迷路外侧壁完好无缺,谨有血管充血。从感染到处死期间未发现动物有前庭紊乱。对照组不受声音刺激。取出膜迷路的椭圆囊、球囊、壶腹和2～3块螺旋器,电镜下观察。结果试验组耳蜗与前庭超微结构都有改变。耳蜗以底转外毛细胞变 Chronic suppurative otitis media has a certain impact on the receptors. Previous experimental studies have found changes in the ultrastructure of cochlear and vestibular receptors in suppurative otitis media. That is due to the middle ear and the relationship between the inner ear vessels, or toxins into the inner ear by getting lost into the two windows. In this paper, two groups of experimental animals in chronic suppurative otitis media conditions under the observation of how the sound cochlear and vestibular receptors. The experimental group (3 rabbits and 4 guinea pigs) and the control group (3 rabbits and 3 guinea pigs) all infected one side of the tympanic membrane with S. aureus, resulting in chronic suppurative otitis media. Animals in the test group were stimulated with 4 kHz, 100 dB of sound for 6 hours and once daily for 5 times. Observation of 6 months, an instant breakage to open the tympanic cavity to remove purulent secretions, see lost outside the wall intact, just like vascular congestion. No animals were found to have vestibular disorders during the period from infection to death. The control group was not acoustically stimulated. Remove the lost capsule of the oval capsule, balloon, ampulla and 2 to 3 pieces of spiral, electron microscopy. Results The cochlear and vestibular ultrastructure of experimental group changed. Cochlear outer hair cells change at the end turn