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目的:探讨未足月胎膜早破的妊娠结局及临床处理方式。方法:对2005年5月~2010年5月胶州市妇幼保健院收治的300例未足月妊娠胎膜早破孕妇的临床资料进行回顾性分析。根据孕周数和所采用的不同治疗手段进行分组,28~35孕周的50例产妇为A组,35孕周以上的150例产妇为B组,每组均包含治疗组和对照组。结果:孕28~36+6周未足月胎膜早破产生的原因很多,包括生殖道病原微生物上行性感染、引/流产史、臀位、羊水过多、性交、妊娠期高血压、不明原因等。未足月胎膜早破是诱发早产,引起新生儿窒息及围生儿死亡的主要原因。但是对于<35孕周的孕妇进行保胎治疗易引起宫内感染。结论:对不同孕周的胎膜早破应采取不同的治疗方法。孕28~35周不伴感染胎膜早破产妇宜采取期待疗法,以达到降低宫内感染发生率,提高新生儿存活率和减少新生儿并发症的目的。
Objective: To investigate the pregnancy outcome and clinical management of preterm premature rupture of membranes. Methods: The clinical data of 300 pregnant women with premature rupture of membranes from May 2005 to May 2010 in Jiaozhou Maternal and Child Health Hospital were analyzed retrospectively. According to the number of gestational weeks and the different treatment groups used, 50 maternal women aged 28-35 gestational weeks were Group A, and 150 maternal women aged 35 weeks or more were Group B, each group containing the treatment group and the control group. Results: Premature rupture of membrane premature rupture occurred in 28 ~ 36 + 6 weeks of gestation. There are many reasons for it, including upward pathogenic microorganisms in genital tract, history of lead / abortion, breech, amniotic fluid, sexual intercourse, gestational hypertension, unknown Reasons and so on. Premature rupture of membranes is induced preterm birth, causing neonatal asphyxia and perinatal death of the main reason. But for pregnant women <35 gestational weeks miscarriage treatment can easily lead to intrauterine infection. Conclusion: Different gestational age premature rupture of membranes should adopt different treatment methods. Pregnancy 28 ~ 35 weeks without infection of premature rupture of membranes should take expectant treatment of pregnant women, in order to reduce the incidence of intrauterine infection, improve neonatal survival rate and reduce neonatal complications.