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目的:探讨肾孤立性纤维瘤(SFT)的临床病理特征及诊断。方法:结合文献复习,对2000年1月~2010年12月我院病理确诊的7例肾SFT患者的临床资料、影像学特征、病理结果进行回顾性分析。结果:7例患者CT平扫提示肾内等密度或低密度软组织圆形或卵圆形肿物,增强有轻中度强化。7例均行根治性肾切除术。肿瘤平均直径10.9(7~19)cm,镜下肿瘤细胞呈束状、旋涡状或不规则状排列,免疫组化CD34、CD39、Vimentin阳性,5例病理确诊为良性肾SFT,2例低度恶性。术后平均随访33.6(24~46)个月,无复发及转移。结论:肾SFT临床罕见,预后好,确诊依靠病理组织学及免疫组化检查。根治性肾切除术和术后长期随访是防止复发和转移的关键。
Objective: To investigate the clinicopathological features and diagnosis of renal solitary fibroma (SFT). Methods: According to the literature review, the clinical data, imaging features and pathological findings of 7 patients with pathologically confirmed SFT in our hospital from January 2000 to December 2010 were analyzed retrospectively. Results: The CT scan of 7 patients showed intrarenal isthmus or low density soft tissue round or oval tumor, enhanced mild to moderate enhancement. Seven patients underwent radical nephrectomy. The average diameter of tumor was 10.9 (7-19) cm. The tumor cells were arranged in bundle, swirl or irregular shape. Immunohistochemistry showed CD34, CD39 and Vimentin positive, and 5 cases were diagnosed as benign renal SFT by pathology. Vicious. After an average follow-up of 33.6 (24 ~ 46) months, no recurrence and metastasis. Conclusion: The clinical manifestations of renal SFT rare, good prognosis, diagnosis depends on histopathology and immunohistochemistry. Radical nephrectomy and postoperative long-term follow-up are key to preventing recurrence and metastasis.