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目的探讨乳腺肉瘤的临床特点、诊治方法及预后,以提高乳腺肉瘤的诊治水平。方法回顾性研究本院自2001年1月~2011年12月的乳腺肉瘤的临床资料。结果本组无手术死亡,2例分叶状囊肉瘤失访,1例癌肉瘤术后失访,另外1例20个月复发后失访。1例高度恶性分叶状囊肉瘤,术后26个月死亡。3例恶性淋巴瘤均在5年内死亡。1例纤维肉瘤18个月后复发,行全乳腺切除术。3例纤维肉瘤(包括1例复发后再次手术)及2例分叶状囊肉瘤(1例低度恶性,1例高度恶性)均健在。结论对术前肿块较大且怀疑可能为乳腺肉瘤的患者尽可能行空心针穿刺取组织学病理及联合免疫组化明确诊断,指导治疗,肉瘤主要以手术为主,预后主要与病理类型及生物学行为关系较密切,肿块大小并不是预后的关键因素,术后内脏转移患者较多。
Objective To investigate the clinical features, diagnosis and treatment of breast sarcoma and prognosis in order to improve the diagnosis and treatment of breast sarcoma. Methods The clinical data of breast sarcoma in our hospital from January 2001 to December 2011 were retrospectively studied. Results There was no operative death in this group, 2 cases of lobated cystic sarcoma were lost, 1 case of carcinosarcoma were lost after operation, and 1 case was lost after 20 months recurrence. One case of highly malignant phyllodes sarcoma died after 26 months. Three cases of malignant lymphoma died within 5 years. One case of fibrosarcoma recurred 18 months later, underwent total mastectomy. Three cases of fibrosarcoma (including one case of reoperation after surgery) and two cases of phylogenetic cystic sarcoma (one case of low grade and one case of high grade) were all present. Conclusions For patients with large preoperative tumor and possibly suspected breast sarcoma, hollow needle aspiration is the best method to diagnose and guide the treatment. The main sarcoma is surgery. The prognosis is mainly related to the pathological type and biological Learning behavior is more closely related to the size of the tumor is not a key factor in prognosis, patients with visceral metastasis more.