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人类T细胞白血病-淋巴瘤病毒(HTLV),首次在美国成人T细胞恶性肿瘤中发现,并从其成熟T细胞分离成功。获得性免疫缺乏综合征(AIDS)患者的T淋巴细胞功能多有损害,表现在淋巴细胞降低,皮肤应变能力差,辅助T细胞亚群(OKT4~+)减少,辅助和抑制T淋巴细胞(OKT4~+/OKT8~+)成反比,淋巴细胞对有丝分裂原反应低,某些病例的自然杀伤细胞活性亦下降。本病常伴巨细胞病毒或乙型肝炎病毒慢性感染;许多病例的血清抗体能与HTLV感染细胞的膜蛋白起反应;现已在33例AIDS病例中有2例检出HTLV的DNA。本文报道3例AIDS从外周血T
Human T-cell leukemia-lymphoma virus (HTLV) was first found in adult human T-cell malignancies in the United States and successfully isolated from its mature T cells. Patients with Acquired Immune Deficiency Syndrome (AIDS) have more damage to T lymphocytes, which is characterized by decreased lymphocytes, poor skin strain, decreased OKT4 ~ (+) T helper cell subsets, and help and suppression of T lymphocytes (OKT4 ~ + / OKT8 ~ +) is inversely proportional to the low response of lymphocytes to mitogens, natural killer cell activity in some cases also decreased. The disease is often accompanied by cytomegalovirus or chronic hepatitis B virus infection; many cases of serum antibodies can react with the membrane protein of HTLV infected cells; now in 33 cases of AIDS, 2 cases detected HTLV DNA. This article reports 3 cases of AIDS from the peripheral blood T