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目的:了解老年糖尿病、冠心病时血脂、肾功能变化与疾病的关系,目前认为老年患者的高尿酸血症常与高血压、高脂血症、糖尿病及冠心病并存。方法:用酶法测定血脂即甘油三脂(TG)总胆固醇(TC)肾功能即尿素氮(BUN)尿酸(UA)肌酐(Cr),同时设置对照组进行比较,探讨老年糖尿病对尿酸代谢影响,并分析老年糖尿病血尿酸(UA)水平与年龄、病程、空腹血糖(FPG)、总胆固醇(TC)、尿素氮(BUN)及肌酐(Cr)的相关性。结果:老年糖尿病UA(mmol/L)水平421.91±107.07较对照组336.01±102.57,P<0.05有统计学意义,TG(mmol/L)1.67±0.81较对照组1.57±0.76,P>0.05无统计学意义,TC(mmol/L)5.53±0.89较对照组4.57±0.85,P<0.05有统计学意义。结论:老年糖尿病合并高血压、高血脂及冠心病时,肾功能,血脂明显高于对照组对临床诊断有较高价值。
OBJECTIVE: To understand the relationship between the changes of blood lipids and renal function in elderly patients with diabetes mellitus and coronary heart disease, and the current prevalence of hyperuricemia in elderly patients and hypertension, hyperlipidemia, diabetes mellitus and coronary heart disease. Methods: Serum lipids, triglyceride (TG), total cholesterol (TC), renal function (BUN) and uric acid creatinine (UA) were measured by enzymatic method and compared with control group to explore the effect of senile diabetes on uric acid metabolism The relationship between serum UA and age, duration of disease, fasting blood glucose (FPG), total cholesterol (TC), blood urea nitrogen (BUN) and creatinine (Cr) were analyzed. Results: Compared with control group, the level of UA (mmol / L) in elderly patients was 421.91 ± 107.07, which was significantly lower than that of control group (336.01 ± 102.57), P <0.05 was statistically significant Significance of the study, TC (mmol / L) 5.53 ± 0.89 than the control group 4.57 ± 0.85, P <0.05 was statistically significant. Conclusion: The elderly patients with diabetes mellitus with hypertension, hyperlipidemia and coronary heart disease, renal function, blood lipids were significantly higher than the control group of high value for clinical diagnosis.